Full list: Google Scholar    Scopus ID   Pubmed    

Selected recent studies

  • Wolosker H. and Radzishevsky, I (2021) Promiscuous enzymes generating d-amino acids in mammals: Why they may still surprise us? Biochem J 478(5):1175-1178.
  • Bodner O, Radzishevsky I, Foltyn VN, Touitou A, Valenta A, Rangel IF, Panizzutti R, Kennedy RT, Billard JM, Wolosker H. (2020) D-Serine signaling and NMDAR-mediated synaptic plasticity are regulated by system A-type of glutamine/D-serine dual transporters Journal of Neurosci. 40(34):6489-6502
  • Balu, D.T., and Wolosker, H. (2020) D-Serine as the gatekeeper of NMDA receptor activity: implications for the pharmacologic management of anxiety disorders. Transl. Psychiatry 9;10(1):184.



  • Neame, S., Safory, H., Radzishevsky, I., Touitou, A., Marchesani, F., Marchetti, M., Kellner, S., Berlin, S., Foltyn, V.N., Billard, J.M., Wolosker H. (2019) The NMDA receptor activation by D-serine and glycine is controlled by an astrocytic Phgdh-dependent serine shuttle. Proc. Natl. Acad. Sci. U S A 116 (41) 20736-20742.


  • Balu, D.T., Presti, K.T., Huang, C.C.Y., Muszynski, J., Radzishevsky, I., Wolosker, H., Guffanti, G., Ressler, K.J., Coyle, J.T.  (2018) Serine Racemase and D-serine in the Amygdala are Dynamically Involved in Fear Learning. Biol. Psychiatry 83(3):273-283.



  • Kaplan, E, Zubedat, S., Radzishevsky, I., Valenta, A.C., Rechnitz, O., Sason, H., Sajrawi, C., Bodner, O., Konno, K., Esaki, K., Derdikman, D. , Yoshikawa, Watanabe, M., Kennedy, R.T., Billard, J.M., Avital, A., Wolosker, H (2018) The ASCT1 (Slc1a4) Transporter is a Physiologic Regulator of Brain D-Serine and Neurodevelopment. Proc. Natl. Acad. Sci. U S A 115(38):9628-9633.


  • Sason, H, Billard, J.M., Smith, G.P., Safory, H., Neame, S., Kaplan, E., Rosenberg, D., Zubedat, S., Foltyn, V.N., Christoffersen, C.T., Bundgaard, C., Thomsen, C., Avital, A., Christensen, K.V., and Wolosker, H. (2017) Asc-1 transporter regulation of synaptic activity via the tonic release of D-serine in the forebrain. Cerebral Cortex 27: 1573-1587.



  • Kolodney, G., Dumin, E., Safory, H., Rosenberg, D, Mori, H., Radzishevsky, I and Wolosker, H. (2015) Nuclear compartmentalization of serine racemase regulates D-serine production: Implications for N-methyl-D-aspartate (NMDA) receptor activation. J. Biol. Chem. 290: 31037-31050.


  • Safory, H., Neame, S., Shulman,Y., Zubedat, S., Radzishevsky, I., Rosenberg, D., Sason, H., Engelender, S., Avital, A., Hülsmann, S., Schiller, J. and Wolosker, H. (2015) The alanine-serine-cysteine-1 (Asc-1) transporter is a regulator of glycine metabolism and glycinergic inhibitory transmission. EMBO Rep. 16(5):590-8.


  • Le Bail, M., Sacchi, S., Yatsenko, N., Martineau, M., Radzishevsky, I., Conrod, S., Ouares,K.A., Wolosker, H., Pollegioni, L., Billard, J.M., Mothet, J.P. (2015) The identity of the NMDA receptor co-agonist is synapse specific and developmentally regulated in the hippocampus. Proc. Natl. Acad. Sci. U S A 112(2):E204-13.


  • Dikopoltsev, E., Foltyn, V.N., Zehl, M., Jensen, O.N., Mori, H., Radzishevsky, I,, and  Wolosker, H. (2014) FBXO22 is Required for Optimal Synthesis of the NMDA Receptor Co-agonist D-Serine J. Biol. Chem. 289(49):33904-15.


  • Ehmsen, J.T., Ma, T.M., Sason, H., Rosenberg, D., Ogo, T., Furuya, S., Snyder, S.H., and Wolosker, H. (2013) D-Serine in Glia and Neurons Derives from 3-Phosphoglycerate Dehydrogenase.  J. Neurosci 33(30):12464-12469.


  • Rosenberg, D., Artoul, S., Segal, A.C., Kolodney, G., Dikopoltsev, E.,  Radzishevsky, I,  Foltyn, V.N., Inoue, R., Mori, H., Billard, J.M., Wolosker, H. (2013) Neuronal D-serine and glycine release through the Asc-1 transporter regulates NMDAR-dependent synaptic activity.  J. Neurosci  33(8): 3533-3544


  • Wolosker H. and Radzishevsky, I (2013) The serine shuttle between glia and neurons: Implications for neurotransmission and neurodegeneration. Biochem. Soc. Trans. 41, 1546-1550.